Effects of Mucuna Milk (Mucuna pruriens L.) on Body Weight and Serum Biochemistry in Rats Fed Hyperlipidaemic Diet
نویسندگان
چکیده
Aims: to investigate the potential of Mucuna milk influence weight gain, blood lipid levels and redox status in a rat model on high-fat diet.
 Study Design: 42 healthy male Wistar rats were randomly divided into 7 groups 6 rats. Group I received standard diet; II was fed high fat diet only; III treated with Atorvastatin (10 mg/kg per day) orally for 4 weeks; IV, V, VI VII tests given 20 mL vegetable milk.
 Methodology: milks produced from two varieties seeds. Three controls (I, II, III) made normal diet, atorvastatin mg/kg/day). In addition, four test (IV, VI, VII) consisting oral administration day at morning 10 afternoon).
 Results: After weeks, had an increase their initial body about 224%, higher abdominal fat. A significant (P<0.05) peroxidation (MDA) liver heart also observed. However, inhibited gain (about 66% reduction) (54.53 – 55.60% reduction). The reduction LDL, VLDL, Triglycerides Total cholesterol remarkable milk, as 67% observed dehulled (DCM, DVM) 69 % whole (WCM, WVM). hyperlipidaemic group ASAT (134.17 UI/L) ALAT (101.72 UI/L). improved MDA (70-50%) related phenolic content milks. Moreover, negative correlations between catalase (r= -0.86; P =0.05); SOD - 0.60; P=0.05).
 Conclusion: This study showed that treatment has anti-hyperlipidaemia properties can activity antioxidant enzymes.
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ژورنال
عنوان ژورنال: European journal of nutrition & food safety
سال: 2022
ISSN: ['2347-5641']
DOI: https://doi.org/10.9734/ejnfs/2022/v14i1030540